Being expressed in newly formed blood vessels of solid cancers but not in normal mature tissues, the extradomain...High CD30 expression in classical Hodgkin's lymphoma and anaplastic large cell lymphoma (ALCL) suggests an important pathogenic role of this cytokine receptor. Although gonadotropins stimulate cAMP production in somatic cells of the follicle, a decrease in intra-oocyte cAMP levels is required for resumption of meiosis in oocytes. Physiologically, CD30 expression is restricted to a few activated lymphocytes in normal lymphoid tissue and a small population of d...Apaf-1, the human C. elegans Ced-4 homologue, plays a crucial role in mitochondrial mediated apoptosis. Therefore, cDNAs coding for Apaf-1 were examined in six lymphoma derived cell lines,...Since structural luteolysis involves deterioration of tissue, the gene expression of matrix-metalloproteinase-1 (MMP-1) and the respective tissue inhibitor of this metalloprotease (TIMP-1) were measured at various times on the day of pro-oestrus and in animals in which the preovulatory prolactin surge was blocked for the duration of 3 cycles by bro...During each reproductive cycle, a preovulatory surge of gonadotropins induces meiotic maturation of the oocyte in the preovulatory follicle followed by ovulation. ChIP-Seq reads obtained after MYC ChIP-Seq and from input controls analyzing 5 BL cell lines (BL41, Blue1, CA46, Ramos, Raji) are illustrated by using the UCSC genome browser (http://genome.ucsc.edu/).
By immunohistochemistry, we analyzed the expression of galectin-1 and galectin-3 in HL and ALCL cases as well as in cell lines, and investigated the pharmacologi...MYC-binding sites in the MS4A1 gene. Facebook gives people the power to share and makes the world more open and connected. Personal e professional vive. ChIP-Seq reads obtained after MYC ChIP-Seq and from input controls analyzing 5 BL cell lines (BL41, Blue1, CA46, Ramos, Raji) are illustrated for the 5′- ends of the NME1 gene by using the UCSC genome browser (http://genome.ucsc.edu/). ChIP-Seq reads obtained after MYC ChIP-Seq and from input controls analyzing 5 BL cell lines (BL41, Blue1, CA46, Ramos, Raji) are illustrated for the 5′- ends of the BYSL gene by using the UCSC genome browser (http://genome.ucsc.edu/).
Burkhard Hirsch is on Facebook. Check out some of the IMDb editors' favorites movies and shows to round out your Watchlist. Several studies have described A20 inactivation by deletion of the A20 locus at 6q23, inactivating mutations, and/or met...Endogenous β-galactose-binding lectins have many biological functions, but their biological significance in Hodgkin lymphoma (HL) and anaplastic large cell lymphoma (ALCL) remains unclear.
Although formation of inositol...The present study was conducted to characterize in vivo the intraadrenal catecholamine (CA) secretion in rats. To...Gonadotropin and TSH receptors represent a subgroup of seven transmembrane-spanning, G protein-coupled receptors with a large extracellular ligand-binding region. Facebook Twitter Pinterest Reddit Telegram LinkedIn Tumblr Vk WhatsApp Line Gmail YouTube. Reads in red map to the forward strand and blue reads to the reverse strand. Crosstalk of both receptors is unknown. We investigated death receptor-mediated apoptosis and CD30/CD95 crosstalk in four CD30-positive cell lines of cutaneous anaplastic large-cell lymphoma (cALCL). Interesting terms are highlighted in red. T...MYC-binding sites in the NPM1 gene.
Burkhard Hirsch (* 29 maggio 1930 a Magdeburgo; † 11 marzo 2020 a Düsseldorf) era un politico tedesco (FDP). ChIP-Seq reads obtained after MYC ChIP-Seq and from input controls analyzing 5 BL cell lines (BL41, Blue1, CA46, Ramos, Raji) are illustrated by using the UCSC genome browser (http://genome.ucsc.edu/). After ligand binding to their receptors, the majority of actions of gonadotropins and TSH are believed to be mediated by the cAMP-protein kinase A pathway. Reads in red map to the forward strand and blue reads to the reverse strand. (XLS)Biological annotations associated with 5,558 of the 7,054 genomic intervals with orthologous regions in at least 4 of 6 mammalian species. This raises the question why caspase-3 does not kill HRS cells. The number of reads within the putative peaks discovered by HOMER and within the final list of 7,054 merged peaks (DESeq) is shown in the far right column. “CD30/CD95 crosstalk analysis” was performed in cALCL cell lines by comparison of CD30 or CD95 stimulation and CD30/CD95 costimulation...Stimulation of the TNF receptors CD30 and CD95 exerts opposite effects. Reads in red map to the forward strand and blue reads to the reverse strand.
Hodgkin/Reed-Sternberg (HRS) cells, the malignant cells of classical Hodgkin's lymphoma (cHL), resist CD95-induced apoptosis. To test this hypothesis, we investigated CD30 signaling in Hodgkin's and ALCL cell lines by different approaches: 1) CD30 stimulation, 2) CD30 down-regulation, and 3) a combination of both....Lymphomatoid papulosis (LyP), primary cutaneous anaplastic large T-cell lymphoma (cALCL), and cutaneous infiltrates of systemic anaplastic large cell lymphoma (sALCL) are CD30-positive lymphoproliferative disorders of the skin that overlap clinically, histopathologically, immunophenotypically, and genetically but differ considerably in their progno...Although the therapy of Hodgkin lymphoma and anaplastic large cell lymphoma has been considerably improved during the last decades, high therapeutic toxicity, relapses, secondary tumors, and primary treatment failure(s) occur.
Secretion and biologic action of these hormones are dependent on the formation of the heterodimer. (XLS)MYC-binding sites in the BYSL gene. The simultaneous detection of multiple somatic mutations in the context of molecular diagnostics of cancer is frequently performed by means of amplicon-based targeted next-generation sequencing (NGS).
This information is largely based on in vitro investigations in which the balance between inhibitory and stimulatory principles involved in the activation of collagenase are largely disrupted.
To analyze the impact of TNFα or IL2 on human lymphocytes in vitro and the anti-tumor and immune-modifying effects of L19-IL2 and L19-TNFα on subcutaneously growing J558L myeloma in immunocompetent mice. All rights reserved.• worked on the signal transduction of gonadotropin receptors
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