0000051750 00000 n This site uses cookies. In the reported cases, these reactions were generally reversible on discontinuation of treatment (see 4.8 Undesirable Effects).Prolonged or repeated courses of aciclovir in severely immune-compromised individuals may result in the selection of virus strains with reduced sensitivity, which may not respond to continued aciclovir treatment (see section 5.1).The risk of renal impairment is increased by use with other nephrotoxic drugs.The data currently available from clinical studies is not sufficient to conclude that treatment with aciclovir reduces the incidence of chickenpox-associated complications in immunocompetent patients.
Consérvese a no más de 30ºC. Plasma protein binding is relatively low (9 to 33%) and drug interactions involving binding site displacement are not anticipated. Forma farmacéutica: Comprimidos Everyday Health is among the federally registered trademarks of Everyday Health, Inc. and may not be used by third parties without explicit permission. after marrow transplant) or in patients with impaired absorption from the gut, consideration should be given to intravenous dosing. In severely immunocompromised patients (e.g. Dosing should begin as early as possible after the start of an infection: Treatment of herpes zoster yields better results if initiated as soon as possible after the onset of the rash. Dosage 400 mg twice daily for 10 days. In severely immunocompromised patients (e.g.

0000016489 00000 n Cerebrospinal fluid levels are approximately 50% of corresponding plasma levels. Acyclovir will not cure herpes, but it can lessen the symptoms of the infection.Acyclovir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chicken pox.Acyclovir may also be used for purposes not listed in this medication guide.You should not take this medicine if you are allergic to acyclovir or valacyclovir (Valtrex).
Acyclovir 400 mg Tablets Unfortunately our full catalog may not be displayed in your state. Capsules: 200 mg. Tablets: 400 and 800 mg. In the treatment of herpes zoster infections it is recommended to adjust the dosage to 800 mg aciclovir twice daily at approximately twelve hourly intervals for patients with severe renal impairment (creatinine clearance less than 10 ml/minute), and to 800 mg aciclovir three times daily at intervals of approximately eight hours for patients with moderate renal impairment (creatinine clearance in the range 10 – 25 ml/minute).

This information is intended for use by health professionalsCapsule shaped biconvex uncoated white to off-white tablets with “400” debossed on one side and “ACV” on the other side.Aciclovir Tablets are indicated for the treatment of herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes (excluding neonatal HSV and severe HSV infections in immunocompromised children). 0000001514 00000 n : Aciclovir ..... 400 mg. Excipientes c.s.p.

A woman which was 6 weeks postpartum received intravenous acyclovir 300 mg (5 mg/kg) 3 times daily for 5 days. Valtrex 500 Mg, 1000 Mg OTC (No RX) Valtrex is an antiviral medicine used of the therapy of herpes viruses. Dosage titration down to 200 mg Aciclovir taken thrice daily at approximately eight-hourly intervals or even twice daily at approximately twelve-hourly intervals may prove effective. Caution is therefore advised if aciclovir is to be administered to a nursing woman. Most of the drug is excreted unchanged by the kidney. Injection: 50 mg/ml.

0000132851 00000 n The enzyme thymidine kinase (TK) of normal, uninfected cells does not use aciclovir effectively as a substrate, hence toxicity of mammalian host cells is low; however, TK encoded by HSV and VZV converts aciclovir to aciclovir monophosphate, a nucleoside analogue which is further converted to the diphosphate and finally to the triphosphate by cellular enzymes. Cerner Multum™ provides the data within some of the Basics, Side Effects, Interactions, and Dosage tabs. Acyclovir passes right into boob milk and also could harm a nursing baby. When aciclovir is given one hour after 1 gram of probenecid the terminal half-life and the area under the plasma concentration time curve is extended by 18% and 40% respectively. How should I keep acyclovir stored? The possibility of renal impairment in the elderly must be considered and the dosage should be adjusted accordingly (see Dosage in renal impairment below). Your dose needs may change if you gain or lose weight.Drink plenty of water while you are taking acyclovir to keep your kidneys working properly.Use this medicine for the full prescribed length of time, even if your symptoms quickly improve.

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